Transcriptional control of embryonic and adult neural progenitor activity

Neural precursors generate neurons in the embryonic brain and restricted niches of adult a process called neurogenesis. The precise control cell proliferation differentiation time space required for neurogenesis depends on sophisticated orchestration gene transcription neural precursor cells. Much progress has been made understanding transcriptional regulation neurogenesis, which relies dose- context-dependent expression specific factors that regulate maintenance progenitors, followed by their into lineage-specified Here, we review some most widely studied neurogenic cortex brain. We compare functions these highlighting biochemical, developmental, biological properties. Our goal is to present an overview underlying developing cerebral